And, according to the ATP, it's the fifth timeFederer lost a match at a major tournament after holding a match point, something else that last happened seven years ago.
That meant Federer had equalled but not bettered his previous best set-winning streak which came between the third round in 2005 and the final in 2006.
The eight-time champion was two sets up and had a match point in the third, but nearly three hours later he trudged off on the end of a seismic 2-6 6-7 (5/7) 7-5 6-4 13-11 upset.
Federer eventually cracked at 11-11, double-faulting to hand Anderson a break point which he converted when the defending champion hit a weary-looking forehand halfway up the net.
Serbia's Djokovic shrugged off a second-set slump to reach a Grand Slam semifinal for the first time since 2016 by beating the Japanese 6-3, 3-6, 6-2, 6-2.
Not only has he yet to drop a set through four matches at the All-England Club this year, but he hasn't had his serve broken, and it wasn't until his last match against Adrian Mannarino that he faced his first break point.
The South African will play in his first Wimbledon quarter-final against a player who's won the tournament a record eight times. "I don't think it's fair but it is what it is".
Switzerland's Roger Federer grimaces after losing a point during the fifth set of his men's quarterfinals match against Kevin Anderson of South Africa at the Wimbledon Tennis Championships, in London, Wednesday July 11, 2018.
Na eases to five-shot PGA Tour victory Tag Ridings (Arkansas Razorbacks) tied for 27th at 11 under, while Sebastian Cappelen (Razorbacks) tied for 41st at 8 under. Kraft said he struggled judging the speed of his putts. "It s nice to get that second trophy". "Hopefully I get this done".
Anderson then held the 24th game to clinch one of tennis' most famous victories. This is Djokovic's second consecutive Wimbledon quarterfinal. If you ask me if I prefer another one, I say yes.
The match was played there after Novak Djokovic, having played three of his opening four matches away from Centre Court, had his request to play in the main stadium granted.
Anderson's attempt to serve out the set was not without drama but, though Federer brought up a break-back point, a searing cross-court backhand saved it and a forehand into the left corner secured a decider.
Federer wasted a match point during the 2-6, 6-7 (5), 7-5, 6-4, 13-11, match.
The other quarter-final features American John Isner and Canadian former runner-up Milos Raonic.
World number one Nadal faces a tricky test against power-hitter del Potro in his first Wimbledon quarter-final since 2011.
Khachanov's display was flashy but full of errors, and Djokovic was ruthless in punishing them, coming through 6-4 6-2 6-2 to set up a last-eight meeting with Kei Nishikori.
But he is already experimenting with different options. "[Croatia] will be tough but I think we're going to get through". The manner of that performance instantly won over the home crowd and gave them a reason to cheer their team.
Speaking to CNN's Erin Burnett on Tuesday, Puerto Rico's governor said he was "appalled and disgusted" by the video. Irizarry had rented a forest preserve pavilion for a birthday party and was issued a permit for the event.
But that's not all Timberlake did to show his support for England as it takes on Croatia in the World Cup semifinal Wednesday. The players have already bettered expectations, with the whole of England buying into the team and their recent performances.
Scotland's Russell Knox beat New Zealand's Ryan Fox on the first hole of a play-off to win the Irish Open . Paul Dunne and Graeme McDowell carded rounds of 71 as they finished on even par for the tournament.
The second semi will take place in Moscow's Luzhniki - also the venue for the final - on Wednesday evening. Statistically speaking, France had Belgium's number when it came to taking shots for most of the game.
Supreme Court is hearing a bunch of petitions challenging a 158-year-old colonial-era law that criminalises gay sex. Tushar Mehta, appearing for the Centre, told the apex court, "We leave it to the wisdom of the court".
Pacific Northwest, and are likely to get sent elsewhere as exporters scramble to avoid paying the tariff, a U.S. trader said. Asian markets appear to have taken in stride the USA move to raise tariffs on billions of dollars of Chinese products.
Next year's Northern Trust will return to Liberty National in Jersey City, New Jersey, before heading to TPC Boston in 2020. After months of teasing , the PGA Tour's return to MI got a name, date and confirmation of location Tuesday.
Zsa Zsa , the floppy-tongued bulldog from Minnesota who won the World's Ugliest Dog contest just last month, has reportedly died. Zsa Zsa was about nine years old when she passed away, which is about the life expectancy for the breed.
NASA’s Kepler Telescope nearly out of fuel, forced to nap
NASA knew that one day Kepler would run out of fuel so NASA plans to start a 19th discrete "observation campaign" of "K2" mission. In that time, the Kepler will wake up and maneuver itself with the remaining fuel so that its antenna will point toward Earth.
Cardi B countersuing her ex-manager for $15M
In April Leonard sued her for $10m , claiming to have "played an integral role in developing her music career and public image". This apparently included her relationships as she claims Shaft would tell her "who she should and should not see romantically".
Leaked Galaxy Tab S4 render reveals the new S Pen
A Korean news site called The Bell and Ice Universe have referred to the alleged new S10s as Beyond 0, Beyond 1 and Beyond 2. In any case, I imagine Samsung is keeping its big redesigns for next year's Note 10, because 10 is a special number and all.
Starbucks is done with plastic straws
Starbucks is the latest corporate chain promising to ditch plastic straws because of the environmental threat to oceans. The new lids are already being used in more than 8,000 stores in North America for beverages such as draft nitro.
Joaquin Phoenix Joker Movie Is Happening
Warner Bros has officially given the green light for a standalone Joker movie, with Joaquin Phoenix in the lead role. A release date hasn't yet been announced, but shooting will begin in September in NY .
Agent of Chelsea Target Alisson Ends Imminent Move Thoughts
And Courtois has re-iterated the importance of being close to his children , though he has no problems with his life in London. Real Madrid are hot on the trail of Courtois, with Paris Saint Germain looking set to land Italian legend Gianluigi Buffon.
Dier inspired by Sterling's handling of criticism
The flak Sterling receives doesn't bother him as much anymore, in his own words, the youngster focussing on his duties instead. Sterling's pace did pose the Swedes issues throughout and Hurst admired the way he frequently got behind England's opponents.
31-under par! LPGA Young gun runs hot
Sei Young Kim has broken the previous 72-hole scoring record on the Tour, with a nine-shot win at the LPGA Classic in Wisconsin. The 25-year-old carded a seven-under-par 65 in the final round, after Thursday's 63, Friday's 65 and Saturday's 64.