Certain blood pressure medications, oral contraceptives, painkillers and even antacids were cited on the list of 200 prescription drugs named in the study that have known potential side effects of depression and even suicide. "Many may be surprised to learn that their medications, despite having nothing to do with mood or anxiety or any other condition normally associated with depression, can increase their risk of experiencing depressive symptoms, and may lead to a depression diagnosis", she said in a statement.
A new study reveals that one-third of Americans are taking both prescription and over-the-counter medications that may raise the risk of depression in some individuals.
The findings are particularly alarming because numerous drugs don't come with warning labels, and are meant for conditions users wouldn't naturally associate with their emotional or mental state.
Numerous drugs are commonplace and not associated with a risk of depression despite the evidence showing their effects.
The report cautioned that "Product labeling for over-the-counter medications does not include comprehensive information on adverse side effects including depression".
The study is cross-sectional, meaning it doesn't conclude that the medications used cause depression, but only that there is an association between the two.
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Researchers at the University of IL at Chicago analyzed the use of medications of more than 26,000 adults from 2005 to 2014 who participated in a larger health and nutrition survey. In the year 2005-2006, 35 percent of the participants had been taking a prescription drug with depression listed as a potential side effect, but less decade a later, in 2013-2014, this figure jumped to 38.4 percent. The researchers have not established any causal relationship between the drugs they identified in the study and depression - they merely pointed out a correlation. Use of three or more drugs concurrently increased from 7 percent to 10 percent, approximately.
According to Allan Young, director of the Center for Affective Disorders at King's College London who was not involved in the study, the "findings seem robust".
"It could be the chronic conditions people are taking the medications for, heart conditions, cancer, is what's really causing the depression, not the drugs", said Dr. Tara Narula.
"Many prescription medicines may have depression as a possible side effect and this should be discussed with patients up front".
Qato says that solutions worth further study may include updating drug safety software to recognize depression as a potential drug-drug interaction, so that health care professionals, including pharmacists, are more likely to notice if a patient is using multiple medications that may increase risk.
The app's ability to predict user behaviour could also be used by Uber drivers to detect user's vulnerability. For example, a rider who has Parkinson's or a hand tremor might be recognized by the app as being drunk.
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