Leaves from the kratom tree, which grows in Southeast Asia and is distantly related to coffee plants, have been touted as a potential treatment for opioid withdrawal, among other conditions.
Kratom has grown in popularity in the US, with circulating claims of it being a safe treatment with a range of healing properties. It's taken recreationally for its euphoric effects, as a dietary supplement, to treat anxiety and depression, and more.
The herbal product has been shown to exert similar effects as opioids, carrying with it similar risks of abuse and addiction.
Kratom also has opioid-like effects - at low doses, it acts like a stimulant; at higher doses, it sedates, dulling pain - which has also made it popular as an over-the-counter remedy for opioid withdrawal.
Meanwhile, a similarly troubling trend has been seen with kratom. The FDA is devoted to expanding the development and use of medical therapy to assist in the treatment of opioid use disorder. The FDA noted a 10-fold increase in calls made to US poison control centers regarding kratom from 2010 to 2015, and reports of 36 deaths linked to the substance.
Importers, organized crime or others in the supply chain could be part of conspiracies to distribute illegal opioids, Sharfstein says.
The FDA's chief, Scott Gottleib, asked Congress for more power and expanded resources to combat the opioid epidemic on Tuesday. The agency also has a team of medical reviewers in the FDA's Center for Drug Evaluation and Research that's dedicated to the proper development of drug applications for botanicals. Gottlieb says the FDA plans to work with the DEA to determine how kratom should be classified.
If companies want to market kratom for its supposed health benefits, they should go through the FDA's drug review process, Gottlieb said.
In 2014, the FDA issued an alert that allowed USA officials to detain kratom without a physical examination.
"This is especially relevant given the public's perception that it can be a safe alternative to prescription opioids", he added.
Meanwhile, the FDA is working to prevent shipments of kratom from entering he country, he said. We've used our authority to conduct seizures and to oversee the voluntary destruction of kratom products. But the DEA almost made kratom a Schedule 1 drug, the same as heroin and marijuana, last year, and the FDA is now trying to stop shipments of kratom from entering the United States while it works on increasing regulatory oversight. Some products have unsafe substances other than kratom in them, including opioids.
"We've learned a tragic lesson from the opioid crisis: that we must pay early attention to the potential for new products to cause addiction, and we must take strong, decisive measures to intervene", Gottlieb said.
The firm has a market cap of $1,678.62, a price-to-earnings ratio of 16.99, a P/E/G ratio of 1.10 and a beta of 1.34. Kulicke and Soffa Industries now has an average rating of "Buy" and an average target price of $26.50. ( KLIC ) .
This is due to ripples created at a much lower frequency, and a novel research has demarcated where and how to start looking. Researchers claim collision of two supermassive black holes will produce powerful gravitational waves .
In taking a look at some key indicators for Cisco Systems, Inc . (NASDAQ: CSCO ), 23 have Buy rating, 0 Sell and 14 Hold. Eqis Cap Management stated it has 0.06% in Enanta Pharmaceuticals Inc (NASDAQ:ENTA). (NASDAQ: CSCO ) for 131,948 shares.
Akash is also very keen on breaking the bond between Vikas and Arshi, as he finds them to be strongest contestants in the house. At the end of the task, Bigg Boss announces that Benafsha, Hina Khan and Sapna are nominated for this week.
You know the guy's a true fan when he talks about the empty feeling we all have when baseball goes away for six months. Some celebrity shows are just about that celebrity and their hobby, but Murray had baseball fans in mind with this.
BidaskClub raised shares of Windstream Holdings from a "sell" rating to a "hold" rating in a research report on Monday, July 31st. This buyback authorization permits the technology company to purchase up to 19.9% of its shares through open market purchases.
A jungle fling? What happens in the jungle stays in the jungle, apart from all the people watching it. The 41-year-old was spotted with his presenting pal as they landed in Australia to front the show.
Court hears appeal in Newtown shooting case
A lower court dismissed the lawsuit past year , ruling that a federal law protects the gun manufacturer. He got it for his 18th birthday ... remember he was 14 years old when they started this marketing plan.
Eve Officially Joins 'The Talk' on CBS
Eve - full name Eve Jeffers Cooper - is taking over the seat vacated by Aisha Tyler , who left the show in July . As an actress, Eve has had roles in "xXx", the " Barbershop " franchise, "Glee", and her self-titled UPN sitcom.
Total War spin-off Thrones of Britannia announced
What are the playable factions? The press release also included a FAQ document with more information on Thrones of Britannia . The game will offer a super-detailed campaign map, with more regional distinction.
Military can question Trump's order to launch nuclear weapons
Some members of Congress are pushing for a check on the president's powers, particularly his ability to order a preemptive strike. When asked before the hearing if he was concerned about Trump's authority, Corker said, "This is not specific to anyone".
Yashwant Sinha hits out at Modi, Jaitley
BJP MP Shatrughan Sinha also came out in support of his party colleague Yashwant Sinha, saying he was a true statesman and had shown the government the mirror.
GameStop temporarily halts unlimited used games program
Kotaku reports that GameStop employees have been instructed to remove signage advertising PowerPass from stores. That means any in-store advertisements for PowerPass have been removed and put in storage until further notice.
(ADP) or Citrix Systems, Inc. (CTXS)?
Moreover, Fernwood Investment Mgmt Ltd Liability Company has 0.41% invested in Automatic Data Processing (NASDAQ: ADP ). The stock of Automatic Data Processing (NASDAQ: ADP ) earned "Hold" rating by Stifel Nicolaus on Monday, January 30.
3 dead, shooter killed near Tehama County school
According to local law enforcement, there were "multiple victims in multiple locations". "Our doors are locked", she said. "I know that we have (airlifted) a number of students", Assistant Sheriff Phil Johnston told NBC-affiliate KCRA .