Carolina Panthers run over San Francisco 49ers in opener

Carolina Panthers v San Francisco 49ers

San Francisco 49ers wide receiver Marquise Goodwin (11) can not catch a pass as he is defended by Carolina Panthers cornerback James Bradberry (24) during the first half of an NFL football game in Santa Clara, Calif., Sunday, Sept. 10, 2017. Newton struggled previous year and coming off an injury, but with dynamic rookie running back Christian McCaffrey with a healthy Kelvin Benjamin and Greg Olsen, Newton has more weapons than he has ever had and will look to exploit the 49ers defense. San Francisco didn't get on the board until late in the third quarter with a 44-yard field goal from Robbie Gould.

The Panthers finished the game against the 49ers with four sacks and eight quarterback hits. The No. 8 overall pick rushed 13 times in his National Football League debut for 47 yards and also caught five passes on seven targets for 38 yards.

Shaq Thompson and Thomas Davis combined for two sacks and three QB hits on Sunday.

The Kyle Shanahan Era for the San Francisco 49ers got off to a rough start. The first-round pick had three tackles and broke up a pass in less than a quarter before getting hurt. Two turnovers and two failed fourth-down attempts put the 49ers defense in hard spots. They also created two takeaways, securing the interception in the second half and recovering a McCaffrey fumble caused by cornerback Rishard Robinson in the fourth quarter.

Thomas was credited with two tackles, including one for loss, in his first game as a pro. Meanwhile, tight end George Kittle is also listed as questionable due to he's also dealing with his recovery from hamstring injury. He mostly succeeded at slowing down Christian McCaffrey, who caught just five passes for 38 yards.

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Because he hadn't completed a pass for more than 20 yards against live competition since last year's season finale in Tampa Bay, no one knew what to expect from Newton. McCaffrey was the Panthers eighth overall pick in the 2017 draft. Since the NFL Realigned in 2002, Carolina and San Francisco have met just six times and once int he playoffs. This isn't a team that's headed for a winning record and, in fact, for quarterback Brian Hoyer, the worst thing that could happen is for the 49ers to reel off a couple of early wins and get expectations up. "He just - his timing isn't there where it needs to be, obviously".

- After major turnover on the 49ers roster, the addition of veteran receiver Pierre Garçon appeared to be crucial for leadership. In a Jets offense that isn't going to be very vertical, Powell will be the at the center of their game plan.

Past year these two teams played in Charlotte and Carolina won easily 46-27 behind more than 500 yards of offense.

So Carolina could afford some mistakes, and made some. Sean McDermott left to become Buffalo's head coach, so Panthers head coach elevated Steve Wilks, former assistant head coach and defensive backs coach, to defensive coordinator.

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